Atlas of Thyroid and Neuroendocrine Tumor Markers 1st ed. 2018 Edition

Atlas of Thyroid and Neuroendocrine Tumor Markers 1st ed. 2018 Edition

By>> Luca Giovanella

 

 

  • Published in 2018
  • 1st Edition
  • Format: pdf
  • Publisher: SPRINGER
  • Number Of pages : 247 pages
  • File size: 8 MB

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About :Download Atlas of Thyroid and Neuroendocrine Tumor Markers 1st ed. 2018 Edition

 

This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up.

Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers.

In this context, effective communication between clinicians and laboratory physicians/scientists is essential in allowing all those involved to fully profit from these exciting advances.

In this comprehensive, up-to-date book, authors from different laboratory and clinical areas link laboratory and clinical topics. Analytical problems such as interferences, false-negative and false-positive results are discussed in depth, and flow-charts offer insights into identifying and avoiding them. Illustrated clinical cases detail the clinical role and limitations of different tumor markers.

Lastly, it explores health technology assessment and economic issues.

This is a valuable resource for endocrinologists, oncologists, nuclear medicine physicians, scientists and technologists who want to keep abreast of the latest developments.

TABLE OF CONTENTS

Part I Pathology and Pathobiology
1 Pathology and Immunohistochemistry in Thyroid Tumors
. . . . . . 3
Esther Diana Rossi and Guido Fadda
2 Pathology of Neuroendocrine Neoplasms: Morphological,
Immunophenotypical, and Circulating Molecular Markers
. . . . . 13
Stefano La Rosa, Massimo Bongiovanni, and Silvia Uccella
3 Circulating Biomarkers: Biological Basis, Methods,and Interpretation Criteria .  . . . . . . . . . . . . 39
Stefan Holdenrieder

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Part II Differentiated Thyroid Cancer
4 Differentiated Thyroid Cancer: Diagnosis,Therapy, and Follow-Up. . .. . . . . . . . . . . . . . . . . 51
Frederik A. Verburg
5 Thyroglobulin and Thyroglobulin Antibodies . . . . . . . . . . . . . . . . 65
Luca Giovanella, Federica D’Aurizio, Renato Tozzoli, Camilla Schalin-Jantti, and Ulla Feldt-Rasmussen
6 Circulating Molecular Biomarkers in Thyroid Cancer. . . . . . . . . 93
Cosimo Durante, Francesca Rosignolo, Marialuisa Sponziello, Antonella Verrienti, and Sebastiano Filetti
7 Circulating Epithelial Tumor Cells in Thyroid Carcinoma . . . . 107
Thomas Winkens, Katharina Pachmann, and Martin Freesmeyer


Part III Medullary Thyroid Carcinoma
8 Medullary Thyroid Carcinoma (MTC): Diagnosis, Treatment and Follow-Up . . . . . .  . . . . . . . . . 119
M. Alevizaki, K. Saltiki, G. Simeakis, and T. Pappa

9 Calcitonin and Carcinoembryonic Antigen for the Diagnosis and Management of Medullary Thyroid Carcinoma . . . . . . . . . . . . . . . . . . . . . . . . . . . 133
Giuseppe Costante, Yassine Lalami, Christiane Jungels, and Ahmad Awada
10 Procalcitonin: Are We Ready for Clinical Use? . . . . . . . . . . . . . . 151
Pierpaolo Trimboli, Alicia Algeciras-Schimnich, and Luca Giovanella


Part IV Aggressive and Rare Thyroid Carcinoma
11 Aggressive Variants of Thyroid Carcinoma . . . . . . . . . . . . . . . . . 161
Massimo Salvatori, Claudio Altini, Luca Zagaria, Alfonso Verrillo, and Germano Perotti
12 Circulating Mucins and Cytokeratins in Aggressive Thyroid Cancers. . . . . . . . . . . . . . . . . . . . . 175
Luca Giovanella, Federica D’Aurizio, and Renato Tozzoli


Part V Thyroid Biomarkers on Fine-Needle Washouts
13 Measurement of Thyroid Tumor Markers on Fine-Needle Washouts . .. . . . . . . . . . . . . . . . . . 193
Pierpaolo Trimboli and Luca Giovanella


Part VI Neuroendocrine Tumors
14 Neuroendocrine Tumours: Diagnosis, Therapy and Follow-up . . . . 203
Diego Ferone, Elena Nazzari, Federica Grillo, Stefania Sciallero, Silvia Morbelli, Franco De Cian, Giuseppe
Cittadini, Manuela Albertelli, and Giannini Edoardo
15 Circulating Markers in Neuroendocrine Tumors . . . . . . . . . . . . 223
Ettore Seregni and Alice Lorenzoni
16 Neuroendocrine Gene Transcripts: The Role of Molecular Biomarkers in Diagnosis and Management . . . . . . . . . . . . . . . . . 235
Lisa Bodei, Mark Kidd, Kyung Min Chung, and Irvin Modlin

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